Slinn Pickings – Chemistry News – Issue 50

  • Cardiff study suggests targeted treatment for leukaemia group – Antibody-directed chemotherapy offers improved survival to particular sub-groups of leukaemia sufferers, a Cardiff University-led study has found. The findings suggest that the treatment may be effective for the majority of younger acute myeloid leukaemia (AML) sufferers, who can be identified by genetic profiling.
  • Nano-sized vaccines – MIT engineers have designed a new type of nanoparticle that could safely and effectively deliver vaccines for diseases such as HIV and malaria.
  • Nanoparticles increase survival after blood loss – In an advance that could improve battlefield and trauma care, scientists at Albert Einstein College of Medicine of Yeshiva University have used tiny particles called nanoparticles to improve survival after life-threatening blood loss. Nanoparticles containing nitric oxide were infused into the bloodstream of hamsters, where they helped maintain blood circulation and protect vital organs.
  • Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment – A key step in mass spectrometry (MS)-based proteomics is the identification of peptides in sequence databases by their fragmentation spectra. Here we describe Andromeda, a novel peptide search engine using a probabilistic scoring model.
  • 3D nanoparticle in atomic resolution – For the first time, scientists from Empa and ETH Zurich have, in collaboration with a Dutch team, managed to measure the atomic structure of individual nanoparticles. The technique, recently published in «Nature», could help better understand the properties of nanoparticles in future.
  • Oak Ridge National Laboratory – ‘Fingerprints’ match molecular simulations with reality – A theoretical technique developed at the Department of Energy's Oak Ridge National Laboratory is bringing supercomputer simulations and experimental results closer together by identifying common "fingerprints."
  • Repairing faulty genes – Israeli scientists have developed compounds that could be better treatments for genetic diseases than current drugs. Timor Baasov and his colleagues at the Israel Institute of Technology have improved compounds used to suppress faults in genes called nonsense mutations.
  • Applied physicists discover that migrating cells flow like glass – By studying cellular movements at the level of both the individual cell and the collective group, applied physicists have discovered that migrating tissues flow very much like colloidal glass. The research, led by investigators at Harvard's School of Engineering and Applied Sciences (SEAS) and the University of Florida, advances scientists' understanding of wound healing, cancer metastasis, and embryonic development.
  • Liquid metal key to simpler creation of electrodes for microfluidic devices – Researchers from North Carolina State University have developed a faster, easier way to create microelectrodes, for use in microfluidic devices, by using liquid metal.
  • Compound Used to Block Cholesterol Could Also Kill Breast Cancer, MU Researcher Finds – A University of Missouri researcher believes there could be a new drug compound that could kill breast cancer cells. The compound might also help with controlling cholesterol.

More chemistry news from chemist Robert Slinn for Reactive Reports in his regular column: Slinn Pickings.