In a previous issue, we discussed early work on Escherichia coli as a proof of principle for understanding how bacterial resistance to antibiotics can emerge. Now, Edward Yu’s team at Iowa State University have taken another step forward in our …
Tag Archives: protein
1000 disease protein structures
Posted by David Bradley
on June 18, 2012
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An interdisciplinary study hinging on X-ray crystallography and nuclear magnetic resonance studies has examined 1000 proteins from more than 40 different human pathogens, including those responsible for plague, anthrax, salmonella, cholera, tuberculosis, leprosy, amoebic dysentery and influenza. Researchers at the …
Drugs used to overcome cancer may also combat antibiotic resistance: McMaster researchers
Posted by Robert Slinn
on January 16, 2012
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Drugs used to overcome cancer may also combat antibiotic resistance: McMaster researchers – The pharmaceutical sector has made a big investment in targeting kinases proteins, so there are a lot of compounds and drugs out there that, although they were …
Scientists Fixate on Ric-8 to Understand Trafficking of Popular Drug Receptor Targets
Posted by Robert Slinn
on January 11, 2012
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Scientists Fixate on Ric-8 to Understand Trafficking of Popular Drug Receptor Targets – Half the drugs used today target a single class of proteins – and now scientists have identified an important molecular player critical to the proper workings of …
Spliced and diced RNA
Posted by David Bradley
on August 3, 2011
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Biomolecular NMR experts in Germany have discovered how the U2AF protein facilitates the process of splicing used by cells to make the correct template for RNA transcription and the subsequent expression of proteins. More on this in my column on …
Unnatural chemicals
Posted by Robert Slinn
on July 8, 2011
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‘Unnatural’ chemical allows Salk researchers to watch protein action in brain cells – Researchers at the Salk Institute have been able to genetically incorporate "unnatural" amino acids, such as those emitting green fluorescence, into neural stem cells, which then differentiate …
